I subscribed to this in MY early 20's way back in the magazines infancy. Back when the cover photo's were black and white and most of the cover "models" were female athletes. It's changed since then, catering a little more to the "Cosmo" crowd. Which is fine, just not for me. It just doesn't feel like it applies as much to someone in their thirties married with kids as someone in their twenties who apparently has the money and lack of self-control to spend $90 on a designer t-shirt (really).
Consult your health care professional. Women of childbearing age may want to consider taking folic acid supplements to reduce the risk of having a pregnancy affected with neural tube defects. Many women and teenage girls don't get enough calcium or vitamin D, both of which are critical to healthy bones and avoiding osteoporosis. Some people with diabetes appear to benefit from chromium. Vegetarians, especially vegans, may want to consider supplements to obtain nutrients they aren't getting from animal products.